Supervised learning-based tagSNP selection for genome-wide disease classifications

Date

2007-07-25

Authors

Liu, Qingzhong
Sung, Andrew H.
Chen, Zhongxue
Yang, Mary Qu
Huang, Xudong
Yang, Jack

Journal Title

Journal ISSN

Volume Title

Publisher

BIomed Central

Abstract

Comprehensive evaluation of common genetic variations through association of single nucleotide polymorphisms (SNPs) with complex human diseases on the genome-wide scale is an active area in human genome research. One of the fundamental questions in a SNP-disease association study is to find an optimal subset of SNPs with predicting power for disease status. To find that subset while reducing study burden in terms of time and costs, one can potentially reconcile information redundancy from associations between SNP markers

Description

The article was originally published by BMC Genomics. doi:10.1186/1471-2164-9-S1-S6

Keywords

association of single nucleotide polymorphisms (SNPs), predicting power, active area

Citation

Liu Q, Yang J, Chen Z, Yang M, Sung AH, Huang X (2008). Supervised-learning based TagSNPs for genome-wide disease classification, BMC Genomics 9 (Suppl 1): S6. doi:10.1186/1471-2164-9-S1-S6