Evaluation of Prolonged Exposure to Pre- and Probiotics in an Avian Model of Treatment-Resistant Depression

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dc.contributor.advisorWhite, Stephen
dc.contributor.authorWillingham, Hannah
dc.date.accessioned2021-07-20T21:12:56Z
dc.date.available2021-07-20T21:12:56Z
dc.date.issued2021-05
dc.descriptionVideo of presentation given at the 2021 Undergraduate Research Symposiumen_US
dc.description.abstractRecent research suggests a link between major depressive disorder (MDD) and changes to the gut microbiome. The purpose of the current study is to evaluate the potential antidepressant effects of probiotics in a model of treatment-resistant depression. Animals will receive either untreated water or water containing probiotics for 14 days. On days 10 and 14, animals will be exposed to an isolation stressor for 90 minutes. Distress vocalizations will be recorded and analyzed to detect group differences. We hypothesize the probiotic treated group will display elevated vocalization rates indicative of an antidepressant effect.en_US
dc.description.sponsorshipUndergraduate Research Symposiumen_US
dc.identifier.urihttps://hdl.handle.net/20.500.11875/3142
dc.subjectMajor depressive disorderen_US
dc.subjectgut microbiomeen_US
dc.subjecttreatment-resistant depressionen_US
dc.subjectAvianen_US
dc.titleEvaluation of Prolonged Exposure to Pre- and Probiotics in an Avian Model of Treatment-Resistant Depressionen_US
dc.typeVideoen_US

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