Polydiacetylene's Effect on Eukaryotic Cell Growth, Viability, and Mutagenesis

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dc.contributor.advisorHarper, James
dc.contributor.advisorGoodspeed, Danielle
dc.contributor.authorChampagne, Rhiannon
dc.date.accessioned2021-07-21T14:45:25Z
dc.date.available2021-07-21T14:45:25Z
dc.date.issued2021-05
dc.descriptionVideo of presentation of research conducted for 2021 Undergraduate Research Symposiumen_US
dc.description.abstractUrinary tract infections (UTIs) are frequent in many healthcare settings and cost the United States billions of dollars in medical spending each year. While UTIs have quickly become more concerning due to resistance to conventional interventions or difficultly in sample collection, development of rapid and effective diagnostic methods have been slow to develop. A possible solution could be to use diapers embedded with a polydiacetylene (PDA) biosensor to detect UTIs. This sensor has the potential to be sensitive and versatile in its detection of uropathogens without the need of a professional to interpret, while causing minimal to no harm to human epithelial cells. Ultimately, the goal of this research was to conclude whether PDA was toxic to eukaryotic cells that are closely related to human epithelial cells. In this poster presentation, we analyzed this potential toxicity with growth, viability, and mutagenesis assays.en_US
dc.description.sponsorshipUndergraduate Research Symposiumen_US
dc.identifier.urihttps://hdl.handle.net/20.500.11875/3148
dc.subjectPolydiacetyleneen_US
dc.subjectGrowthen_US
dc.subjectViabilityen_US
dc.subjectMutagenesisen_US
dc.titlePolydiacetylene's Effect on Eukaryotic Cell Growth, Viability, and Mutagenesisen_US
dc.typeVideoen_US

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